US Patent No. 7,863,896 issued Jan 4, 2011 Systems and Methods for Calibrating Functional Magnetic Resonance Imaging of Living Tissue.
Functional MRI (fMRI) of the brain traditionally is analyzed by contrasting statistically the MRI signals obtained while the person engages is a task versus the signals obtained when the person is not engaged in that task. The figure of merit in such activation analysis is often a dimensionless unit such as correlation coefficient, t‐statistic or F‐statistic. The patent describes apparatus and a method for establishing equivalent strengths of each person’s activations in physical units such as micro‐Tesla or milliamp‐turns per meter. This is intended to promote comparisons across individuals, across tasks, or across imaging platforms by quantifying sensitivity and specificity, with a longrange goal of increased clinical utility for fMRI applications.